INT130000

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Context Info
Confidence 0.49
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.15
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Col1a1) extracellular region (Col1a1) proteinaceous extracellular matrix (Col1a1)
cytoplasm (Col1a1)
Anatomy Link Frequency
nociceptor 2
Col1a1 (Mus musculus)
Pain Link Frequency Relevance Heat
nociceptor 1 100.00 Very High Very High Very High
Inflammatory response 1 97.44 Very High Very High Very High
Disease Link Frequency Relevance Heat
Cramps 1 98.24 Very High Very High Very High
Urological Neuroanatomy 1 97.92 Very High Very High Very High
INFLAMMATION 1 97.24 Very High Very High Very High
Phenylketonuria 8 92.60 High High
Congenital Anomalies 1 77.12 Quite High
Cognitive Disorder 1 68.24 Quite High
Pigment Disorder 1 66.12 Quite High
Dementia 1 65.24 Quite High
Metabolic Disorder 1 59.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Four are involved in defense and inflammatory responses of neutrophils (NE, MPO, NGP, and CRAMP), three other overexpressed genes are related to extracellular matrix organization and degradation (COL1A1, COL1A2, and MMP13); the remainder were a nociceptor in sensory neurons (MrgA1), a structural gene of P lysozyme (Lzp-s), an immunoglobulin alpha heavy chain constant region gene (Igh-2), an osteocalcin-related protein precursor (Bglap-rs1), and a membrane-spanning 4 domain, subfamily A, member 3 (Ms4a3).
Positive_regulation (gene) of Protein_catabolism (degradation) of COL1A1 in nociceptor associated with cramps, inflammatory response, nociceptor and urological neuroanatomy
1) Confidence 0.49 Published 2005 Journal Mol. Genet. Metab. Section Abstract Doc Link 16150627 Disease Relevance 1.15 Pain Relevance 0.15

General Comments

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