INT130138

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Context Info
Confidence 0.06
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.32
Pain Relevance 0.78

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TNF, S100A10) extracellular space (TNF) extracellular region (TNF)
plasma membrane (TNF) intracellular (TNF) extracellular matrix organization (TNF)
Anatomy Link Frequency
BEAS-2B 4
TNF (Homo sapiens)
S100A10 (Homo sapiens)
Pain Link Frequency Relevance Heat
dexamethasone 14 99.90 Very High Very High Very High
Inflammation 6 94.52 High High
cINOD 2 86.96 High High
Disease Link Frequency Relevance Heat
Cancer 2 100.00 Very High Very High Very High
Necrosis 2 100.00 Very High Very High Very High
Adenocarcinoma 2 99.20 Very High Very High Very High
INFLAMMATION 8 94.52 High High
Disease 2 88.84 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here, we investigated the ability of dexamethasone (Dex) to inhibit p-Ser10 expression in response to tumor necrosis factor (TNF-alpha) in the human lung adenocarcinoma cell line A549 and the SV-40-transformed human airway epithelial cell line BEAS-2B.
tumor necrosis factor Negative_regulation (inhibit) of Gene_expression (expression) of p-Ser10 in BEAS-2B associated with adenocarcinoma, necrosis, cancer and dexamethasone
1) Confidence 0.06 Published 2005 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 16165091 Disease Relevance 0.66 Pain Relevance 0.39
Here, we investigated the ability of dexamethasone (Dex) to inhibit p-Ser10 expression in response to tumor necrosis factor (TNF-alpha) in the human lung adenocarcinoma cell line A549 and the SV-40-transformed human airway epithelial cell line BEAS-2B.
TNF-alpha Negative_regulation (inhibit) of Gene_expression (expression) of p-Ser10 in BEAS-2B associated with adenocarcinoma, necrosis, cancer and dexamethasone
2) Confidence 0.06 Published 2005 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 16165091 Disease Relevance 0.66 Pain Relevance 0.39

General Comments

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