INT130139

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Context Info
Confidence 0.38
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.43
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (S100A10)
Anatomy Link Frequency
fibroblasts 2
A549 2
S100A10 (Homo sapiens)
Pain Link Frequency Relevance Heat
dexamethasone 7 99.12 Very High Very High Very High
Inflammation 3 84.92 Quite High
cINOD 1 77.36 Quite High
cytokine 8 49.20 Quite Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
fibrosis 3 5.00 Very Low Very Low Very Low
pain pelvic 2 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 21 99.58 Very High Very High Very High
Adenocarcinoma 1 94.72 High High
Necrosis 1 92.64 High High
Cancer 3 92.28 High High
INFLAMMATION 5 84.92 Quite High
Disease 1 79.24 Quite High
Adhesions 127 78.08 Quite High
Injury 15 66.32 Quite High
Apoptosis 16 39.16 Quite Low
Wound Healing 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hypoxic conditions elevated expression levels of COL4A2, S100A10 and hMT-Ie transcripts in the normal peritoneal fibroblasts (Figure 4).
Negative_regulation (levels) of Gene_expression (expression) of S100A10 in fibroblasts associated with hypoxia
1) Confidence 0.38 Published 2005 Journal Reprod Biol Endocrinol Section Body Doc Link PMC548295 Disease Relevance 0.78 Pain Relevance 0
By Western blot analysis in BEAS-2B cells, the expression of p-Ser10 was repressed by pretreatment with Dex, an effect not seen in A549 cells.
Negative_regulation (repressed) of Gene_expression (expression) of p-Ser10 in A549 associated with dexamethasone
2) Confidence 0.07 Published 2005 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 16165091 Disease Relevance 0.66 Pain Relevance 0.47

General Comments

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