INT130158

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Context Info
Confidence 0.20
First Reported 2006
Last Reported 2006
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

response to stress (Crhr1) signal transducer activity (Crhr1) cell-cell signaling (Pomc)
cytoplasm (Pomc) extracellular space (Pomc) generation of precursor metabolites and energy (Pomc)
Anatomy Link Frequency
brain 2
Pomc (Rattus norvegicus)
Crhr1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Opioid 3 100.00 Very High Very High Very High
Hippocampus 2 98.28 Very High Very High Very High
Enkephalin 1 80.48 Quite High
Intracerebroventricular 1 78.16 Quite High
Potency 1 77.92 Quite High
Endogenous opioid 1 72.96 Quite High
Neuropeptide 1 53.60 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Anti-beta-endorphin IgG down-regulated ET-A receptor protein expression in the caudate (51%), but had no effect on the expression of mu, delta, kappa opioid, ET-B, CRH-1 and CRH-2 receptors in any brain region.
beta-endorphin Neg (no) Regulation (effect) of Gene_expression (expression) of CRH-1 in brain associated with opioid
1) Confidence 0.20 Published 2006 Journal Peptides Section Abstract Doc Link 16165252 Disease Relevance 0 Pain Relevance 0.52

General Comments

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