INT130161

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Context Info
Confidence 0.01
First Reported 2006
Last Reported 2006
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Crhr1) response to stress (Crhr1) signal transducer activity (Crhr1)
Anatomy Link Frequency
brain 2
IgG-2a (Rattus norvegicus)
Crhr1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Opioid 3 100.00 Very High Very High Very High
Hippocampus 2 97.68 Very High Very High Very High
Enkephalin 1 80.48 Quite High
Potency 1 77.92 Quite High
Intracerebroventricular 1 77.56 Quite High
Endogenous opioid 1 72.36 Quite High
Neuropeptide 1 53.60 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Anti-beta-endorphin IgG down-regulated ET-A receptor protein expression in the caudate (51%), but had no effect on the expression of mu, delta, kappa opioid, ET-B, CRH-1 and CRH-2 receptors in any brain region.
IgG Neg (no) Positive_regulation (effect) of Gene_expression (expression) of CRH-1 in brain associated with opioid
1) Confidence 0.01 Published 2006 Journal Peptides Section Abstract Doc Link 16165252 Disease Relevance 0 Pain Relevance 0.52

General Comments

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