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Context Info
Confidence 0.25
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Pomc, Edn1) extracellular region (Pomc, Edn1) cell-cell signaling (Pomc, Edn1)
cytoplasm (Pomc, Edn1) signal transduction (Pomc) generation of precursor metabolites and energy (Pomc)
Pomc (Rattus norvegicus)
Edn1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Opioid 3 97.60 Very High Very High Very High
Enkephalin 1 94.00 High High
Potency 1 92.72 High High
Hippocampus 2 89.84 High High
Intracerebroventricular 1 69.72 Quite High
Endogenous opioid 1 64.52 Quite High
Neuropeptide 1 61.12 Quite High


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Anti-beta-endorphin IgG increased tissue ET-1 levels in the caudate by 30.3%. [35S]GTP-gamma-S binding assays demonstrated that anti-beta-endorphin IgG increased the efficacy of [D-Ala2-MePhe4, Gly-ol5]enkephalin without altering its potency in caudate.
beta-endorphin Positive_regulation (increased) of Gene_expression (levels) of ET-1 associated with enkephalin and potency
1) Confidence 0.25 Published 2006 Journal Peptides Section Abstract Doc Link 16165252 Disease Relevance 0 Pain Relevance 0.58

General Comments

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