INT130187

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Context Info
Confidence 0.35
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.61
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (B2m)
B2m (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 19 99.80 Very High Very High Very High
cytokine 6 99.28 Very High Very High Very High
Inflammatory response 5 98.88 Very High Very High Very High
Pain 1 87.44 High High
Central nervous system 11 5.00 Very Low Very Low Very Low
chemokine 5 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
fifth nerve 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 53 100.00 Very High Very High Very High
INFLAMMATION 24 99.80 Very High Very High Very High
Amyloidosis 5 99.16 Very High Very High Very High
Togavirus Infection 75 95.40 Very High Very High Very High
Arthralgia 1 87.44 High High
Disease 9 66.36 Quite High
Urological Neuroanatomy 2 19.52 Low Low
Apoptosis 16 5.00 Very Low Very Low Very Low
Hypersensitivity 4 5.00 Very Low Very Low Very Low
Gliosis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Some genes related to the inflammatory response, such as Cxcl10, Clu and antigen presentation, such as B2m, Fcer1g showed over-expression only at 72 and 96 hr post infection (Fig 2).
Negative_regulation (infection) of Gene_expression (over) of B2m associated with inflammatory response and infection
1) Confidence 0.35 Published 2008 Journal BMC Genomics Section Body Doc Link PMC2440554 Disease Relevance 0.91 Pain Relevance 0.05
Lixelle treatments reduce the circulating levels of beta2-m and inflammatory cytokines, thereby improving the symptoms of patients with DRA.
Negative_regulation (reduce) of Gene_expression (levels) of beta2-m associated with amyloidosis, inflammation and cytokine
2) Confidence 0.09 Published 2005 Journal Biochim. Biophys. Acta Section Abstract Doc Link 16168723 Disease Relevance 0.70 Pain Relevance 0.28

General Comments

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