INT130227

Context Info Confidence 0.01 First Reported 2005 Last Reported 2005 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 1.39 Pain Relevance 0.70

extracellular region (Olfml3) molecular_function (Olfml3) cellular_component (Olfml3) biological_process (Olfml3)

Anatomy Link Frequency macrophage 2 Olfml3 (Mus musculus)

Pain Link Frequency Relevance Heat Neuritis 6 99.00 Inflammation 3 87.68 cytokine 2 86.36

Disease Link Frequency Relevance Heat Experimental Autoimmune Neuritis 6 99.00 Syndrome 6 98.98 Disease 2 88.00 INFLAMMATION 3 87.68 Autoimmune Disease 1 85.28 Demyelinating Disease 1 5.00

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Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Therefore, to evaluate the role of macrophage migration inhibitory factor (MIF) in Guillain-Barré syndrome (GBS) and experimental allergic neuritis (EAN), we determined MIF circulating levels in a series of patients with GBS and healthy subjects with ELISA and evaluated the effect of two specific inhibitors of MIF, a neutralizing monoclonal antibody or a chemical inhibitor ISO1 on the course of murine EAN.

Regulation (effect) of Negative_regulation (inhibitors) of ISO1 in macrophage associated with experimental autoimmune neuritis, syndrome and neuritis

1) Confidence 0.01 Published 2005 Journal J. Neuroimmunol. Section Abstract Doc Link 16171874 Disease Relevance 1.39 Pain Relevance 0.70

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