INT130283

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Context Info
Confidence 0.10
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.79

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Npy) extracellular region (Npy) aging (Cyp3a23/3a1)
endoplasmic reticulum (Cyp3a23/3a1)
Cyp3a23/3a1 (Rattus norvegicus)
Npy (Rattus norvegicus)
Pain Link Frequency Relevance Heat
dexamethasone 5 100.00 Very High Very High Very High
sodium channel 1 97.48 Very High Very High Very High
tetrodotoxin 3 96.56 Very High Very High Very High
Action potential 1 93.68 High High
Neuropeptide 2 89.36 High High
GABAergic 3 75.00 Quite High
gABA 2 71.20 Quite High
agonist 1 58.88 Quite High
antagonist 2 45.04 Quite Low
Intracerebroventricular 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Hyperinsulinism 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Dexamethasone (DEX) (10(-9) to 10(-7) M) significantly increased NPY mRNA expression, and the effects were not influenced by coincubation with the sodium channel blocker tetrodotoxin (TTX), indicating that the action of DEX is independent of action potentials.
DEX Positive_regulation (increased) of Transcription (expression) of NPY associated with action potential, tetrodotoxin, sodium channel and dexamethasone
1) Confidence 0.10 Published 2005 Journal J. Neurosci. Section Abstract Doc Link 16177033 Disease Relevance 0 Pain Relevance 0.79

General Comments

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