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Context Info
Confidence 0.24
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0.79

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intracellular (IL10) cell-cell signaling (IL10) response to stress (IL10)
signal transducer activity (MC1R) pigmentation (MC1R) extracellular space (IL10)
Anatomy Link Frequency
monocytes 2
MC1R (Homo sapiens)
IL10 (Homo sapiens)
Pain Link Frequency Relevance Heat
melanocortin 1 receptor 12 100.00 Very High Very High Very High
Disease Link Frequency Relevance Heat
Alagille Syndrome 1 69.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Anti-IL-10 Abs failed to prevent suppression by alphaMSH, indicating that it was not due to MC1R-mediated IL-10 release by monocytes.
MC1R Positive_regulation (mediated) of Localization (release) of IL-10 in monocytes associated with melanocortin 1 receptor
1) Confidence 0.24 Published 2005 Journal J. Immunol. Section Abstract Doc Link 16177130 Disease Relevance 0.07 Pain Relevance 0.79

General Comments

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