INT130288

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Context Info
Confidence 0.01
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.10
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (POMC) cell-cell signaling (POMC) cytoplasm (POMC)
extracellular space (POMC) generation of precursor metabolites and energy (POMC) signal transduction (POMC)
Anatomy Link Frequency
monocytes 2
POMC (Homo sapiens)
VTCN1 (Homo sapiens)
Pain Link Frequency Relevance Heat
melanocortin 1 receptor 12 99.18 Very High Very High Very High
Disease Link Frequency Relevance Heat
Alagille Syndrome 1 95.28 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Human PBMCs, including monocytes, express the melanocortin 1 receptor (MC1R), and it is thought that the ability of alphaMSH to alter monocyte-costimulatory molecule expression and IL-10 release is mediated by this receptor.
alphaMSH Regulation (alter) of Gene_expression (expression) of monocyte-costimulatory molecule in monocytes associated with melanocortin 1 receptor
1) Confidence 0.01 Published 2005 Journal J. Immunol. Section Abstract Doc Link 16177130 Disease Relevance 0.10 Pain Relevance 0.59

General Comments

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