INT130321

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Context Info
Confidence 0.56
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.35
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Grm4) plasma membrane (Grm4) intracellular (Grm4)
signal transducer activity (Grm4)
Anatomy Link Frequency
neuronal 1
Grm4 (Mus musculus)
Pain Link Frequency Relevance Heat
palliative 1 98.76 Very High Very High Very High
agonist 1 96.02 Very High Very High Very High
Central nervous system 2 90.88 High High
Glutamate receptor 2 87.08 High High
Disease Link Frequency Relevance Heat
Epilepsy 1 99.96 Very High Very High Very High
Disease 2 99.42 Very High Very High Very High
Neurodegenerative Disease 1 71.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recently, selective agonist or allosteric potentiators of mGluR4, one of the group III mGluRs, have been proposed as potential novel therapeutics for the palliative treatment of Parkinson's disease and some forms of epilepsy. mGluR4 stands out amongst the group III mGluRs due to its relatively restricted localization and apparent role in several key neuronal circuits.
Localization (localization) of mGluR4 in neuronal associated with epilepsy, agonist, disease and palliative
1) Confidence 0.56 Published 2005 Journal Curr Top Med Chem Section Abstract Doc Link 16178733 Disease Relevance 0.35 Pain Relevance 0.31

General Comments

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