INT130425

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Context Info
Confidence 0.43
First Reported 2005
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.57
Pain Relevance 0.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lyase activity (Adcy1) plasma membrane (Adcy1) nucleus (Adcy1)
Adcy1 (Mus musculus)
Pain Link Frequency Relevance Heat
allodynia 28 94.08 High High
opioid receptor 1 90.84 High High
agonist 2 85.04 High High
withdrawal 5 81.92 Quite High
Anterior cingulate cortex 21 78.56 Quite High
halothane 2 75.12 Quite High
opiate 1 74.76 Quite High
Pain 35 57.52 Quite High
isoflurane 1 37.84 Quite Low
Inflammation 18 35.20 Quite Low
Disease Link Frequency Relevance Heat
Bordatella Infection 1 94.32 High High
Neuropathic Pain 29 94.08 High High
Body Weight 5 88.00 High High
Myalgia 29 57.52 Quite High
INFLAMMATION 18 35.20 Quite Low
Nociception 11 33.88 Quite Low
Targeted Disruption 45 5.00 Very Low Very Low Very Low
Pain 10 5.00 Very Low Very Low Very Low
Inflammatory Pain 9 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Intraperitoneal injection of AC1 inhibitor
Negative_regulation (injection) of Negative_regulation (inhibitor) of AC1
1) Confidence 0.43 Published 2006 Journal Mol Pain Section Body Doc Link PMC1395303 Disease Relevance 0.48 Pain Relevance 0.45
In addition, we show that proteins that interfere with the activity of Gbetagamma subunits (Gbetagamma scavengers) strongly attenuate the acute inhibition of AC-I and -VIII and the superactivation of AC-I, and abolish the superactivation of AC-VIII.
Negative_regulation (attenuate) of Negative_regulation (inhibition) of AC-I
2) Confidence 0.04 Published 2005 Journal J. Mol. Neurosci. Section Abstract Doc Link 16186630 Disease Relevance 0.09 Pain Relevance 0.20

General Comments

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