INT130437

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Context Info
Confidence 0.25
First Reported 2005
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.97
Pain Relevance 1.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Nqo1) oxidoreductase activity (Nqo1) aging (Nqo1)
cytoplasm (Nqo1)
Anatomy Link Frequency
sensory system 1
Nqo1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neuropathic pain 2 99.68 Very High Very High Very High
agonist 6 98.72 Very High Very High Very High
nMDA receptor 2 97.76 Very High Very High Very High
nMDA receptor antagonist 2 96.60 Very High Very High Very High
trigeminal ganglion 5 94.68 High High
Spinal cord 2 88.24 High High
Pain 2 87.36 High High
Inflammation 6 85.24 High High
IPN 1 75.00 Quite High
nociceptor 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 2 99.68 Very High Very High Very High
Ganglion Cysts 5 94.24 High High
Nociception 2 92.60 High High
Pain 2 87.36 High High
INFLAMMATION 4 85.24 High High
Inflammatory Pain 1 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To assess the possible roles of NO in trigeminal sensory system, we examined the distribution and density of histochemical staining for nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-d), a marker for nitric oxide synthase (NOS), and immunohistochemical staining for c-Fos, a neuronal activity marker, in the trigeminal ganglion (TG) and trigeminal nucleus caudalis (Vc) following pulp exposure (PX) injured rats.
Phosphorylation (phosphate) of diaphorase in sensory system associated with ganglion cysts and trigeminal ganglion
1) Confidence 0.25 Published 2009 Journal Brain research reviews Section Abstract Doc Link 19013482 Disease Relevance 0.50 Pain Relevance 0.24
Phosphorylation of MARCKS and NADPH-diaphorase activity stimulated by the EP3 agonist were also blocked by H-1152.
Phosphorylation (Phosphorylation) of NADPH-diaphorase associated with agonist
2) Confidence 0.01 Published 2005 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 16188227 Disease Relevance 0.20 Pain Relevance 0.44
These phosphorylation and nNOS activity visualized by NADPH-diaphorase histochemistry were blocked by indomethacin, a PG synthesis inhibitor.
Phosphorylation (phosphorylation) of NADPH-diaphorase
3) Confidence 0.01 Published 2005 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 16188227 Disease Relevance 0.27 Pain Relevance 0.46

General Comments

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