INT130474

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Context Info
Confidence 0.45
First Reported 2005
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.73
Pain Relevance 1.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ptger1) plasma membrane (Ptger1) signal transducer activity (Ptger1)
Ptger1 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 3 100.00 Very High Very High Very High
Neuropathic pain 8 97.36 Very High Very High Very High
agonist 1 96.64 Very High Very High Very High
Spinal cord 4 96.16 Very High Very High Very High
Dorsal horn 2 89.04 High High
Neuronal nitric oxide synthase 1 86.84 High High
nMDA receptor 4 79.52 Quite High
Pain 4 56.08 Quite High
Inflammation 16 5.00 Very Low Very Low Very Low
cINOD 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 8 97.36 Very High Very High Very High
Malignant Neoplastic Disease 44 97.24 Very High Very High Very High
Cancer 60 82.00 Quite High
Nervous System Injury 1 75.76 Quite High
Endometriosis (extended) 3 74.32 Quite High
Ovarian Diseases 2 70.24 Quite High
Pain 1 56.08 Quite High
Cyst 11 42.24 Quite Low
Adenoma 1 12.64 Low Low
Adenocarcinoma 3 10.12 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Indomethacin, an inhibitor of prostaglandin (PG) synthesis, and PGE receptor subtype EP1-selective antagonist reduced the NR2B phosphorylation in these mice.
Phosphorylation (phosphorylation) of PGE receptor associated with antagonist
1) Confidence 0.45 Published 2005 Journal Eur. J. Neurosci. Section Abstract Doc Link 16190898 Disease Relevance 0.67 Pain Relevance 1.22
The additional Mr species most likely represents phosphorylated forms of mPGES-1 and EP1–2.
Phosphorylation (phosphorylated) of EP1
2) Confidence 0.28 Published 2006 Journal Mol Cancer Section Body Doc Link PMC1657027 Disease Relevance 1.06 Pain Relevance 0

General Comments

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