INT130625

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.23
First Reported 2005
Last Reported 2008
Negated 0
Speculated 3
Reported most in Abstract
Documents 1
Total Number 4
Disease Relevance 1.32
Pain Relevance 3.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Prkcg, Prkaca) plasma membrane (Prkcg, Prkaca) nucleus (Prkcg, Prkaca)
cytoplasm (Prkcg, Prkaca) nucleoplasm (Prkaca) mitochondrion (Prkaca)
Anatomy Link Frequency
heart 2
spinal cord 1
Prkcg (Rattus norvegicus)
Prkaca (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Kinase C 38 100.00 Very High Very High Very High
Spinal cord 15 99.12 Very High Very High Very High
narcan 6 98.96 Very High Very High Very High
central sensitization 13 98.64 Very High Very High Very High
Morphine 12 98.28 Very High Very High Very High
Pain 11 98.24 Very High Very High Very High
withdrawal 10 97.92 Very High Very High Very High
spinothalamic 3 97.48 Very High Very High Very High
Inflammation 11 97.44 Very High Very High Very High
qutenza 31 87.52 High High
Disease Link Frequency Relevance Heat
Nociception 23 99.40 Very High Very High Very High
Pain 7 98.24 Very High Very High Very High
INFLAMMATION 9 97.44 Very High Very High Very High
Hypersensitivity 1 97.20 Very High Very High Very High
Hyperalgesia 4 75.00 Quite High
Nervous System Injury 1 25.24 Quite Low
Injury 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The present study was designed to investigate the possible changes of protein kinase A (PKA) and different isoforms of protein kinase C (PKC): PKC alpha, PKC delta and PKC zeta after naloxone induced morphine withdrawal in the heart.
PKC Spec (possible) Regulation (changes) of PKA in heart associated with kinase c, narcan, withdrawal and morphine
1) Confidence 0.23 Published 2005 Journal Eur. J. Pharmacol. Section Abstract Doc Link 16202991 Disease Relevance 0 Pain Relevance 1.17
The present study was designed to investigate the possible changes of protein kinase A (PKA) and different isoforms of protein kinase C (PKC): PKC alpha, PKC delta and PKC zeta after naloxone induced morphine withdrawal in the heart.
PKC Spec (possible) Regulation (changes) of PKA in heart associated with kinase c, narcan, withdrawal and morphine
2) Confidence 0.23 Published 2005 Journal Eur. J. Pharmacol. Section Abstract Doc Link 16202991 Disease Relevance 0 Pain Relevance 1.16
The aim of the present study was to investigate the peripheral involvement of PKA and PKC in persistent nociceptive response, evoked pain behaviors, and inflammation induced by subcutaneous (s.c.) injection of bee venom (BV, 0.2mg/50 microl) in rats.
PKC Spec (investigate) Regulation (involvement) of PKA associated with nociception, pain and inflammation
3) Confidence 0.20 Published 2008 Journal Pain Section Abstract Doc Link 17544210 Disease Relevance 1.06 Pain Relevance 0.54
Experiments from behavioral studies also support the roles of PKA and PKC in the generation of spinal cord central sensitization [2,15,19].
PKC Regulation (roles) of PKA in spinal cord associated with kinase c, central sensitization and spinal cord
4) Confidence 0.04 Published 2005 Journal Mol Pain Section Body Doc Link PMC1224868 Disease Relevance 0.26 Pain Relevance 1.00

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox