INT130648

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Context Info
Confidence 0.05
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.05
Pain Relevance 2.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Cyba) mitochondrion (Cyba) oxidoreductase activity (Cyba)
Golgi apparatus (Cyba) cytoplasm (Cyba)
Cyba (Mus musculus)
Pain Link Frequency Relevance Heat
local anesthetic 24 99.98 Very High Very High Very High
lidocaine 2 94.48 High High
Inflammation 2 53.52 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 2 53.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, tetracaine and the other local anesthetics inhibit by disparate mechanisms, but all the local anesthetics impaired up-regulation of cytochrome b558 and all impaired priming of NADPH oxidase by LPS.
Negative_regulation (impaired) of Positive_regulation (up-regulation) of cytochrome b558 associated with local anesthetic
1) Confidence 0.05 Published 2005 Journal J. Leukoc. Biol. Section Abstract Doc Link 16204644 Disease Relevance 0 Pain Relevance 0.91
Local anesthetics inhibited LPS-induced up-regulation of cytochrome b558 but not LPS-induced translocation of p47phox.
Negative_regulation (inhibited) of Positive_regulation (up-regulation) of cytochrome b558 associated with local anesthetic
2) Confidence 0.03 Published 2005 Journal J. Leukoc. Biol. Section Abstract Doc Link 16204644 Disease Relevance 0.05 Pain Relevance 1.09

General Comments

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