INT130651

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Context Info
Confidence 0.41
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Title
Documents 2
Total Number 2
Disease Relevance 0.99
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Cyba) mitochondrion (Cyba) oxidoreductase activity (Cyba)
Golgi apparatus (Cyba) cytoplasm (Cyba)
Anatomy Link Frequency
microglial cell 1
neutrophils 1
Cyba (Mus musculus)
Pain Link Frequency Relevance Heat
local anesthetic 12 98.96 Very High Very High Very High
Inflammation 4 97.84 Very High Very High Very High
lidocaine 1 56.76 Quite High
cva 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 4 97.84 Very High Very High Very High
Stroke 2 89.40 High High
Disease 2 88.56 High High
Neurodegenerative Disease 2 75.92 Quite High
Brain Injury 53 69.84 Quite High
Injury 3 58.32 Quite High
Apoptosis 4 55.84 Quite High
Contusions 5 52.20 Quite High
Death 5 5.00 Very Low Very Low Very Low
Stress 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We then demonstrated that the microglial phenotypes expressed both gp91phox and p22phox, which probably reflects the induction of NADPH oxidase in the BV-2 mouse microglial cell line that we used.
Gene_expression (expressed) of p22phox in microglial cell
1) Confidence 0.41 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2917406 Disease Relevance 0.89 Pain Relevance 0
Local anesthetics inhibit priming of neutrophils by lipopolysaccharide for enhanced release of superoxide: suppression of cytochrome b558 expression by disparate mechanisms.
Gene_expression (expression) of cytochrome b558 in neutrophils associated with local anesthetic
2) Confidence 0.06 Published 2005 Journal J. Leukoc. Biol. Section Title Doc Link 16204644 Disease Relevance 0.10 Pain Relevance 0.68

General Comments

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