INT130690

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Context Info
Confidence 0.21
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.58
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (HSPA5, DDIT3) nucleoplasm (DDIT3) unfolded protein binding (HSPA5)
endoplasmic reticulum (HSPA5) DNA binding (DDIT3) protein binding, bridging (HSPA5)
HSPA5 (Homo sapiens)
DDIT3 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 6 60.60 Quite High
Disease Link Frequency Relevance Heat
Apoptosis 7 100.00 Very High Very High Very High
Cancer 4 71.40 Quite High
Stomach Cancer 1 59.52 Quite High
INFLAMMATION 1 43.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Overexpression of GRP78 partially suppressed the apoptosis and induction of CHOP in the presence of celecoxib and this suppression was stimulated by coexpression of either ERdj3 or ERdj4.
Gene_expression (Overexpression) of GRP78 Negative_regulation (suppressed) of Positive_regulation (induction) of CHOP associated with apoptosis
1) Confidence 0.21 Published 2006 Journal Oncogene Section Abstract Doc Link 16205636 Disease Relevance 0.58 Pain Relevance 0.17

General Comments

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