INT130701

Context Info Confidence 0.50 First Reported 2006 Last Reported 2006 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.50 Pain Relevance 0.05

unfolded protein binding (HSPA5) endoplasmic reticulum (HSPA5) ATPase activity (HSPA5) nucleus (HSPA5) protein binding, bridging (HSPA5)

HSPA5 (Homo sapiens)

Pain Link Frequency Relevance Heat cINOD 6 52.32

Disease Link Frequency Relevance Heat Apoptosis 7 98.32 Cancer 4 63.12 Stomach Cancer 1 51.24 INFLAMMATION 1 34.92

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

On the other hand, suppression of GRP78 expression by siRNA drastically stimulated cellular apoptosis and production of CHOP in the presence of celecoxib.

Negative_regulation (suppression) of Gene_expression (expression) of GRP78 associated with apoptosis

1) Confidence 0.50 Published 2006 Journal Oncogene Section Abstract Doc Link 16205636 Disease Relevance 0.50 Pain Relevance 0.05

General Comments

This test has worked.