INT130712

Context Info Confidence 0.33 First Reported 2006 Last Reported 2006 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.75 Pain Relevance 0.43

nucleoplasm (ATF4) DNA binding (ATF4) microtubule organizing center (ATF4) cytoplasm (ATF4) nucleus (ATF4) cytoskeleton (ATF4)

ATF4 (Homo sapiens)

Pain Link Frequency Relevance Heat cINOD 6 80.00

Disease Link Frequency Relevance Heat Cancer 4 90.80 Apoptosis 7 86.88 Stomach Cancer 1 78.92 INFLAMMATION 1 62.60

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Suppression of ATF4 expression by small interfering RNA (siRNA) partially inhibited the celecoxib-dependent upregulation of GRP78.

Negative_regulation (Suppression) of Gene_expression (expression) of ATF4

1) Confidence 0.33 Published 2006 Journal Oncogene Section Abstract Doc Link 16205636 Disease Relevance 0.75 Pain Relevance 0.43

General Comments

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