INT130750

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Context Info
Confidence 0.41
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.82

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (CYP2B6) endoplasmic reticulum (CYP2B6)
CYP2B6 (Homo sapiens)
Pain Link Frequency Relevance Heat
Bioavailability 5 99.48 Very High Very High Very High
methadone 8 98.72 Very High Very High Very High
Opioid 1 97.32 Very High Very High Very High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effects of inhibiting cytochrome P450 3A, p-glycoprotein, and gastric acid secretion on the oral bioavailability of methadone in dogs.
Negative_regulation (inhibiting) of Localization (secretion) of P450 associated with methadone and bioavailability
1) Confidence 0.41 Published 2005 Journal J. Vet. Pharmacol. Ther. Section Title Doc Link 16207309 Disease Relevance 0 Pain Relevance 0.82

General Comments

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