INT130799

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Context Info
Confidence 0.63
First Reported 2005
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.94
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Fgf23) extracellular space (Fgf23)
Anatomy Link Frequency
fibroblast 1
Fgf23 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 5 79.52 Quite High
Fibrositis 1 49.00 Quite Low
Disease Link Frequency Relevance Heat
Rickets 4 100.00 Very High Very High Very High
Cancer 1 100.00 Very High Very High Very High
Familial Hypophosphatemia 11 99.84 Very High Very High Very High
Osteoporosis 6 91.04 High High
Alkalosis 1 86.36 High High
Acidosis 1 80.00 Quite High
Pain 4 79.52 Quite High
Low Back Pain 1 67.16 Quite High
Bone Cancer 1 58.04 Quite High
Hypophosphatemia 1 57.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
FGF23 seems not be a cause of IPD, and the FGF23/phosphate/1-25(OH)2D3 axis appeared to be functional.
Localization (cause) of FGF23 associated with familial hypophosphatemia
1) Confidence 0.63 Published 2009 Journal Calcif. Tissue Int. Section Abstract Doc Link 19148564 Disease Relevance 0.89 Pain Relevance 0.08
The most extensively studied phosphatonin to date is fibroblast growth factor 23 (FGF23), which was first identified in patients with tumor-induced osteomalacia and shown to be secreted by the neoplastic cells.
Localization (secreted) of FGF23 in fibroblast associated with rickets and cancer
2) Confidence 0.35 Published 2005 Journal Joint Bone Spine Section Abstract Doc Link 16214071 Disease Relevance 1.04 Pain Relevance 0.20

General Comments

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