INT130801

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Context Info
Confidence 0.28
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 5
Disease Relevance 2.41
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (SFRP4) extracellular space (SFRP4) extracellular region (SFRP4)
nucleus (SFRP4) embryo development (SFRP4) cytoplasm (SFRP4)
Anatomy Link Frequency
fallopian tubes 1
SFRP4 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 11 89.68 High High
endometriosis 92 88.08 High High
cINOD 4 72.40 Quite High
Pain 6 47.72 Quite Low
metalloproteinase 14 26.52 Quite Low
Inflammation 7 5.00 Very Low Very Low Very Low
cytokine 5 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
pain pelvic 2 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 58 93.04 High High
Rickets 8 88.56 High High
Endometriosis 131 88.08 High High
Disease 51 82.16 Quite High
Familial Hypophosphatemia 4 75.00 Quite High
Disease Progression 1 72.64 Quite High
INFLAMMATION 10 71.88 Quite High
Alkalosis 2 66.52 Quite High
Carcinoma 24 62.12 Quite High
Acidosis 2 60.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Other phosphatonins may exist, such as matrix extracellular phosphoglycoprotein (MEPE) and secreted frizzled-related protein 4 (SFRP4), whose role remains to be defined.
Localization (secreted) of secreted frizzled-related protein 4
1) Confidence 0.28 Published 2005 Journal Joint Bone Spine Section Abstract Doc Link 16214071 Disease Relevance 0.46 Pain Relevance 0
Other phosphatonins may exist, such as matrix extracellular phosphoglycoprotein (MEPE) and secreted frizzled-related protein 4 (SFRP4), whose role remains to be defined.
Localization (secreted) of SFRP4
2) Confidence 0.28 Published 2005 Journal Joint Bone Spine Section Abstract Doc Link 16214071 Disease Relevance 0.46 Pain Relevance 0
The Wnt-Frizzled interaction can be antagonized by several secreted proteins, including Dickkopf1 (Dkk1), Wnt inhibitory factor 1(WIF-1) and secreted frizzled-related protein (sFRP) family members.
Localization (secreted) of sFRP
3) Confidence 0.09 Published 2010 Journal J Hematol Oncol Section Body Doc Link PMC2954871 Disease Relevance 0.44 Pain Relevance 0.19
The Wnt-Frizzled interaction can be antagonized by several secreted proteins, including Dickkopf1 (Dkk1), Wnt inhibitory factor 1(WIF-1) and secreted frizzled-related protein (sFRP) family members.
Localization (secreted) of sFRP
4) Confidence 0.09 Published 2010 Journal J Hematol Oncol Section Body Doc Link PMC2954871 Disease Relevance 0.42 Pain Relevance 0.18
It has been suggested that communication and transfer between the peritoneal and uterine cavities occurs in both directions, such that factors secreted in the peritoneal fluid, which baths the reproduction organs, enters the fallopian tubes and reaches the endometrium.
Localization (secreted) of endometrium in fallopian tubes
5) Confidence 0.01 Published 2006 Journal Reprod Biol Endocrinol Section Body Doc Link PMC1775067 Disease Relevance 0.64 Pain Relevance 0.11

General Comments

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