INT130802

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Context Info
Confidence 0.17
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.78
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (FGF23) extracellular space (FGF23) extracellular region (FGF23)
Anatomy Link Frequency
fibroblast 1
FGF23 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 4 68.72 Quite High
Somatostatin 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rickets 77 100.00 Very High Very High Very High
Cancer 13 100.00 Very High Very High Very High
Syndrome 4 98.42 Very High Very High Very High
Alkalosis 1 87.52 High High
Acidosis 1 81.16 Quite High
Familial Hypophosphatemia 5 75.00 Quite High
Pain 3 68.72 Quite High
Low Back Pain 1 68.32 Quite High
Osteoporosis 1 67.00 Quite High
Hypophosphatemia 12 58.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The most extensively studied phosphatonin to date is fibroblast growth factor 23 (FGF23), which was first identified in patients with tumor-induced osteomalacia and shown to be secreted by the neoplastic cells.
Localization (secreted) of fibroblast growth factor 23 in fibroblast associated with rickets and cancer
1) Confidence 0.17 Published 2005 Journal Joint Bone Spine Section Abstract Doc Link 16214071 Disease Relevance 1.05 Pain Relevance 0.20
A further spin-off from the renewed interest in the syndromes has been the development of better diagnostic procedures for the detection of phosphatonin-secreting tumours.



Localization (secreting) of phosphatonin associated with cancer and syndrome
2) Confidence 0.06 Published 2008 Journal Eur J Pediatr Section Body Doc Link PMC2668657 Disease Relevance 0.73 Pain Relevance 0

General Comments

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