INT130803

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Context Info
Confidence 0.17
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.82
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Cdkn2a) aging (Cdkn2a) DNA binding (Cdkn2a)
protein complex (Cdkn2a) cytoplasm (Cdkn2a) signal transducer activity (MC1R)
Anatomy Link Frequency
skin 2
MC1R (Homo sapiens)
Cdkn2a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
melanocortin 1 receptor 4 100.00 Very High Very High Very High
Disease Link Frequency Relevance Heat
Nevus 3 100.00 Very High Very High Very High
Sunburn 2 100.00 Very High Very High Very High
Skin Cancer 6 98.48 Very High Very High Very High
Dysplastic Nevus Syndrome 3 84.24 Quite High
Disease 1 48.40 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Penetrance of CDKN2A gene was found to be significantly influenced by host factors (nevus phenotypes and sunburn) on one hand and by variants of MC1R gene (RHC variants consistently associated with red hair and fair skin) on the other hand.
MC1R Regulation (influenced) of Positive_regulation (Penetrance) of CDKN2A gene in skin associated with melanocortin 1 receptor, sunburn and nevus
1) Confidence 0.17 Published 2005 Journal Cancer Epidemiol. Biomarkers Prev. Section Abstract Doc Link 16214921 Disease Relevance 0.82 Pain Relevance 0.34

General Comments

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