INT130891

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Context Info
Confidence 0.38
First Reported 2005
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.38
Pain Relevance 0.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Mdk) extracellular region (Mdk)
Anatomy Link Frequency
spinal cords 2
lymphocytes 2
Mdk (Mus musculus)
Pain Link Frequency Relevance Heat
Acupuncture 1 100.00 Very High Very High Very High
analgesia 1 100.00 Very High Very High Very High
electroacupuncture 2 96.24 Very High Very High Very High
Spinal cord 17 90.56 High High
Inflammation 9 83.28 Quite High
Thermal hyperalgesia 19 74.68 Quite High
intrathecal 6 68.52 Quite High
Eae 11 50.00 Quite Low
member 8 2 37.68 Quite Low
monoamine 2 26.40 Quite Low
Disease Link Frequency Relevance Heat
Reprotox - General 1 94 99.48 Very High Very High Very High
Cancer 14 96.96 Very High Very High Very High
Nociception 19 89.24 High High
INFLAMMATION 9 83.28 Quite High
Death 10 75.76 Quite High
Hyperalgesia 21 74.68 Quite High
Hypoxia 1 59.84 Quite High
Inflammatory Pain 8 50.00 Quite Low
Apoptosis 4 23.44 Low Low
Pain 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although basal phosphorylated ERK is minimal in mouse spinal cords without noxious stimuli, we investigated whether expression of the DN MEK transgene would alter basal ERK activation in the DN MEK mice.
Spec (whether) Regulation (alter) of Spec (whether) Gene_expression (expression) of DN MEK in spinal cords
1) Confidence 0.38 Published 2006 Journal Mol Pain Section Body Doc Link PMC1382249 Disease Relevance 0.52 Pain Relevance 0.41
We studied the effect of acupuncture analgesia on the expression of ppENKmRNA, MEK-IR, and Dyn-IR in circulating mouse lymphocytes.
Regulation (effect) of Gene_expression (expression) of MEK-IR in lymphocytes associated with acupuncture and analgesia
2) Confidence 0.31 Published 2005 Journal Bull. Exp. Biol. Med. Section Abstract Doc Link 16224585 Disease Relevance 0 Pain Relevance 0.24
MDK expression is negatively regulated by androgen [65].
Regulation (regulated) of Gene_expression (expression) of MDK
3) Confidence 0.22 Published 2010 Journal BMC Med Genomics Section Body Doc Link PMC2956710 Disease Relevance 0.86 Pain Relevance 0

General Comments

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