INT130918

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Context Info
Confidence 0.04
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.37
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (HMHA1, BAX) lipid binding (BAX) mitochondrion (BAX)
endoplasmic reticulum (BAX) nucleus (BAX) cytoplasm (BAX)
Anatomy Link Frequency
cleavage 1
HMHA1 (Homo sapiens)
BAX (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 2 71.88 Quite High
Disease Link Frequency Relevance Heat
Apoptosis 10 100.00 Very High Very High Very High
Colon Cancer 4 88.84 High High
Death 2 86.64 High High
Familial Adenomatous Polyposis 1 80.80 Quite High
Cancer 1 77.36 Quite High
Necrosis 1 76.88 Quite High
INFLAMMATION 1 71.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Coadministration of sulindac sulfide and the small-molecule Bcl-2 inhibitor HA14-1 increased apoptosis induction and enhanced caspase-8 and caspase-9 cleavage, Bax redistribution, and cytochrome c and second mitochondria-derived activator of caspase release.
HA14-1 Positive_regulation (enhanced) of Bax in cleavage associated with apoptosis
1) Confidence 0.04 Published 2005 Journal Mol. Cancer Ther. Section Abstract Doc Link 16227396 Disease Relevance 1.37 Pain Relevance 0.14

General Comments

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