INT130925

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Context Info
Confidence 0.86
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.37
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CYCS) transport (CYCS) mitochondrion (CYCS)
small molecule metabolic process (CYCS) nucleus (CYCS)
Anatomy Link Frequency
cleavage 1
CYCS (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 2 68.92 Quite High
Disease Link Frequency Relevance Heat
Apoptosis 10 99.04 Very High Very High Very High
Death 2 89.28 High High
Colon Cancer 4 85.88 High High
Cancer 1 80.00 Quite High
Necrosis 1 79.52 Quite High
Familial Adenomatous Polyposis 1 77.84 Quite High
INFLAMMATION 1 68.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Coadministration of sulindac sulfide and the small-molecule Bcl-2 inhibitor HA14-1 increased apoptosis induction and enhanced caspase-8 and caspase-9 cleavage, Bax redistribution, and cytochrome c and second mitochondria-derived activator of caspase release.
Protein_catabolism (cleavage) of cytochrome c in cleavage associated with apoptosis
1) Confidence 0.86 Published 2005 Journal Mol. Cancer Ther. Section Abstract Doc Link 16227396 Disease Relevance 1.37 Pain Relevance 0.14

General Comments

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