INT130966

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.36
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.24
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeletal protein binding (EZR) cytosol (EZR) nucleolus (EZR)
plasma membrane (EZR) intracellular (EZR) cytoplasm (EZR)
Anatomy Link Frequency
vesicle 2
EZR (Homo sapiens)
Pain Link Frequency Relevance Heat
dorsal root ganglion 1 85.84 High High
nociceptor 2 83.60 Quite High
Root ganglion neuron 1 81.84 Quite High
Kinase C 1 74.32 Quite High
Mechanosensation 2 74.24 Quite High
Pain 1 70.16 Quite High
Peripheral nervous system 1 68.96 Quite High
ASIC 1 63.72 Quite High
Inflammation 2 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 2 85.84 High High
Pain 1 70.16 Quite High
Toxicity 22 5.00 Very Low Very Low Very Low
Anaerobic Bacterial Infections 12 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Cancer 6 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Drug Induced Neurotoxicity 4 5.00 Very Low Very Low Very Low
Renal Disease 4 5.00 Very Low Very Low Very Low
Brain Hemorrhage 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the presence of NHERF-1, the ASIC3 subcellular localization is modified, and the channel co-localizes with ezrin, a member of the ezrin-radixin-moesin family of actin-binding proteins, providing the first direct link between ASIC3 and the cortical cytoskeleton.
ezrin Binding (co-localizes) of
1) Confidence 0.36 Published 2006 Journal J. Biol. Chem. Section Abstract Doc Link 16234233 Disease Relevance 0.24 Pain Relevance 0.41
Abbreviations: cA, caveolae open to the abluminal front; cC, cytoplasmic caveolae; cL, caveolae open to the luminal surface of the cerebral endothelial cells; cpA, clathrin-coated pit open to the abluminal front; cpL, clathrin-coated pit open to the luminal front; cvA, clathrin-coated vesicle associated with the abluminal endothelial surface; cvL, clathrin-coated vesicle associated with the luminal endothelial surface; V, smooth vesicle; VA, smooth vesicle open to the abluminal front; VL, smooth vesicle open to the luminal front; j, tight junction; te, transcytotic endosome
cvL Binding (associated) of in vesicle
2) Confidence 0.02 Published 2008 Journal AAPS J Section Body Doc Link PMC2761699 Disease Relevance 0 Pain Relevance 0
Abbreviations: cA, caveolae open to the abluminal front; cC, cytoplasmic caveolae; cL, caveolae open to the luminal surface of the cerebral endothelial cells; cpA, clathrin-coated pit open to the abluminal front; cpL, clathrin-coated pit open to the luminal front; cvA, clathrin-coated vesicle associated with the abluminal endothelial surface; cvL, clathrin-coated vesicle associated with the luminal endothelial surface; V, smooth vesicle; VA, smooth vesicle open to the abluminal front; VL, smooth vesicle open to the luminal front; j, tight junction; te, transcytotic endosome
cvL Binding (associated) of in vesicle
3) Confidence 0.02 Published 2008 Journal AAPS J Section Body Doc Link PMC2761699 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox