INT130974

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Context Info
Confidence 0.08
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.29
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Slc9a3r1, ASIC3) cytoplasm (Slc9a3r1, ASIC3) signal transduction (ASIC3)
transport (ASIC3) nucleus (Slc9a3r1)
Anatomy Link Frequency
plasma 1
Slc9a3r1 (Rattus norvegicus)
ASIC3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Root ganglion neuron 1 99.92 Very High Very High Very High
dorsal root ganglion 1 97.92 Very High Very High Very High
Kinase C 1 92.40 High High
Mechanosensation 2 90.28 High High
Pain 1 88.24 High High
Peripheral nervous system 1 87.04 High High
ASIC 1 81.80 Quite High
nociceptor 2 47.68 Quite Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 2 99.60 Very High Very High Very High
Pain 1 88.24 High High
Nociception 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NHERF-1 enhances the ASIC3 peak current in heterologous cells, including F-11 dorsal root ganglion cells, by increasing the amount of channel at the plasma membrane.
NHERF-1 Positive_regulation (enhances) of ASIC3 in plasma associated with ganglion cysts and dorsal root ganglion
1) Confidence 0.08 Published 2006 Journal J. Biol. Chem. Section Abstract Doc Link 16234233 Disease Relevance 0.29 Pain Relevance 0.36

General Comments

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