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Context Info
Confidence 0.02
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.76
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (EDN3) extracellular space (EDN3) extracellular region (EDN3)
cell-cell signaling (EDN3)
Anatomy Link Frequency
endothelial cells 2
EDN3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 8 99.72 Very High Very High Very High
Migraine 5 75.00 Quite High
Calcitonin gene-related peptide 1 67.76 Quite High
Disease Link Frequency Relevance Heat
Neurogenic Inflammation 8 99.72 Very High Very High Very High
Increased Venous Pressure Under Development 6 98.68 Very High Very High Very High
Headache 5 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The release of tachykinins and endothelin-3 (ET-3) from trigeminal neurons induces dural vascular permeability and vasodilatation via activation of tachykinin receptor 1 (Tacr1) and endothelin receptor type B (Ednrb) on endothelial cells.
Positive_regulation (induces) of Localization (release) of ET-3 in endothelial cells associated with increased venous pressure under development
1) Confidence 0.02 Published 2005 Journal Mol. Interv. Section Abstract Doc Link 16249526 Disease Relevance 0.76 Pain Relevance 0.31

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