INT131140

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Context Info
Confidence 0.37
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.58
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (ACO1) mitochondrion (ACO1) lyase activity (ACO1)
Golgi apparatus (ACO1) endoplasmic reticulum (ACO1) RNA binding (ACO1)
Anatomy Link Frequency
outflow 2
ACO1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Analgesic 1 86.72 High High
Glutamate 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Poisoning 6 99.62 Very High Very High Very High
Toxicity 1 88.16 High High
Death 1 82.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Antidotal therapy for FA intoxication has been aimed at preventing fluorocitrate synthesis and aconitase blockade in mitochondria, and at providing citrate outflow from this organelle.
Negative_regulation (preventing) of Negative_regulation (blockade) of aconitase in outflow associated with poisoning
1) Confidence 0.37 Published 2006 Journal J Appl Toxicol Section Abstract Doc Link 16252258 Disease Relevance 0.58 Pain Relevance 0.09

General Comments

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