INT131163

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Context Info
Confidence 0.01
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.60
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Cd2) cell adhesion (CD58) plasma membrane (CD58)
protein complex (Cd2)
Anatomy Link Frequency
effector T cells 2
CD58 (Homo sapiens)
Cd2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
headache 1 60.64 Quite High
pruritus 1 53.92 Quite High
psoriasis 1 26.96 Quite Low
Disease Link Frequency Relevance Heat
Psoriasis 2 99.78 Very High Very High Very High
Headache 1 60.64 Quite High
Nasopharyngitis 1 59.84 Quite High
Rhinitis 1 58.48 Quite High
Influenza Virus Infection 1 57.68 Quite High
Common Cold 1 56.80 Quite High
Pruritus 1 53.92 Quite High
Arthralgia 1 53.12 Quite High
Fatigue 1 52.08 Quite High
Vomiting 1 51.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Alefacept is a selective immunomodulating, antipsoriatic drug that blocks the LFA-3/CD2 interaction necessary for the activation and proliferation of memory effector T cells by binding to CD2 expressed on the T cell surface.
Negative_regulation (blocks) of LFA-3 Binding (interaction) of CD2 in effector T cells associated with psoriasis
1) Confidence 0.01 Published 2005 Journal Expert Opin Drug Saf Section Abstract Doc Link 16255657 Disease Relevance 0.60 Pain Relevance 0.09

General Comments

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