INT131318

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Context Info
Confidence 0.35
First Reported 2006
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 4
Total Number 6
Disease Relevance 3.33
Pain Relevance 1.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeletal protein binding (Fabp3) cytosol (Fabp3) mitochondrion (Fabp3)
cytoplasm (Fabp3)
Anatomy Link Frequency
heart 3
Fabp3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
ischemia 9 98.16 Very High Very High Very High
Angina 10 90.72 High High
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 4 98.16 Very High Very High Very High
Coronary Artery Disease 5 97.88 Very High Very High Very High
Acute Coronary Syndrome 7 97.44 Very High Very High Very High
Necrosis 6 97.12 Very High Very High Very High
Myocardial Infarction 14 96.48 Very High Very High Very High
Angina 8 90.72 High High
Cv General 3 Under Development 2 88.40 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Unbound free fatty acids (FFA(u)) and their intracellular binding protein, heart-type fatty acid-binding protein (H-FABP), have been suggested to have clinical utility as indicators of cardiac ischemia and necrosis, respectively.
H-FABP Binding (binding) of in heart associated with necrosis, coronary artery disease and ischemia
1) Confidence 0.35 Published 2006 Journal Clin. Chem. Section Abstract Doc Link 16269514 Disease Relevance 0.73 Pain Relevance 0.32
This study was prospectively designed to examine whether the combination of H-FABP, a marker for ongoing myocardial damage, and ischemia-modified albumin (IMA), a marker for myocardial ischemia, would effectively diagnose patients with ACS.
H-FABP Spec (whether) Binding (combination) of associated with acute coronary syndrome, coronary artery disease and ischemia
2) Confidence 0.34 Published 2009 Journal J. Clin. Lab. Anal. Section Abstract Doc Link 19140206 Disease Relevance 0.88 Pain Relevance 0.26
Unbound free fatty acids (FFA(u)) and their intracellular binding protein, heart-type fatty acid-binding protein (H-FABP), have been suggested to have clinical utility as indicators of cardiac ischemia and necrosis, respectively.
heart-type fatty acid-binding protein Binding (binding) of in heart associated with necrosis, coronary artery disease and ischemia
3) Confidence 0.30 Published 2006 Journal Clin. Chem. Section Abstract Doc Link 16269514 Disease Relevance 0.73 Pain Relevance 0.32
Specificities of cTnT, CK-MB, myoglobin, H-FABP (by ELISA), H-FABP (by LTIA), and ECG were 98.1%, 71.7%, 81.1%, 77.4%, 90.6%, and 92.5%, respectively.
H-FABP Binding (Specificities) of
4) Confidence 0.26 Published 2010 Journal Am. J. Clin. Pathol. Section Abstract Doc Link 20551280 Disease Relevance 0.40 Pain Relevance 0.08
Specificities of cTnT, CK-MB, myoglobin, H-FABP (by ELISA), H-FABP (by LTIA), and ECG were 98.1%, 71.7%, 81.1%, 77.4%, 90.6%, and 92.5%, respectively.
H-FABP Binding (Specificities) of
5) Confidence 0.26 Published 2010 Journal Am. J. Clin. Pathol. Section Abstract Doc Link 20551280 Disease Relevance 0.40 Pain Relevance 0.08
Patients were assessed on admission: clinical characteristics, ECG (electrocardiogram), renal function, cardiac troponin T (cTnT), heart fatty acid binding protein (H-FABP), glycogen phosphorylase-BB, NT-pro-brain natriuretic peptide, D-dimer, hsCRP (high sensitivity C-reactive protein), myeloperoxidase, matrix metalloproteinase-9, pregnancy associated plasma protein-A, soluble CD40 ligand.
H-FABP Binding (binding) of in heart
6) Confidence 0.16 Published 2008 Journal Eur. Heart J. Section Body Doc Link 18682444 Disease Relevance 0.17 Pain Relevance 0

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