INT131394

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Context Info
Confidence 0.43
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.89
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Ugt1a6) enzyme binding (Ugt1a6) protein complex (Ugt1a6)
Ugt1a6 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cINOD 1 87.92 High High
Inflammatory mediators 3 87.12 High High
dexamethasone 1 85.92 High High
Inflammatory response 5 85.16 High High
Inflammation 88 82.20 Quite High
cytokine 14 28.48 Quite Low
antidepressant 4 5.00 Very Low Very Low Very Low
Analgesic 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Periodontitis 60 100.00 Very High Very High Very High
INFLAMMATION 95 87.52 High High
Periodontal Disease 18 47.84 Quite Low
Adhesions 12 37.72 Quite Low
Mouth Disease 2 23.28 Low Low
Alveolar Bone Loss 14 5.00 Very Low Very Low Very Low
Apoptosis 12 5.00 Very Low Very Low Very Low
Injury 10 5.00 Very Low Very Low Very Low
Infection 10 5.00 Very Low Very Low Very Low
Bacterial Respiratory Disease 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, this endotoxin-induced increase in UGT1A6 expression level was blocked by actinomycin D and cycloheximide, indicating the requirement for RNA and protein synthesis.
Negative_regulation (blocked) of Gene_expression (expression) of UGT1A6
1) Confidence 0.43 Published 2006 Journal Neuropharmacology Section Abstract Doc Link 16274708 Disease Relevance 0.49 Pain Relevance 0.36
In contrast Hypericum treatment prevented the periodontitis-mediated Bax expression (Figure 7a, a1).
Negative_regulation (prevented) of Gene_expression (expression) of a1 associated with periodontitis
2) Confidence 0.04 Published 2010 Journal BMC Complement Altern Med Section Body Doc Link PMC3000377 Disease Relevance 0.17 Pain Relevance 0
In contrast Hypericum treatment prevented the periodontitis-mediated iNOS expression (Figure 6a, a1).
Negative_regulation (prevented) of Gene_expression (expression) of a1 associated with periodontitis
3) Confidence 0.04 Published 2010 Journal BMC Complement Altern Med Section Body Doc Link PMC3000377 Disease Relevance 0.23 Pain Relevance 0.03

General Comments

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