INT131421

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Context Info
Confidence 0.74
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 9
Total Number 9
Disease Relevance 4.30
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (INPP5K) endoplasmic reticulum (INPP5K) plasma membrane (INPP5K)
nucleus (INPP5K) cytoplasm (INPP5K)
Anatomy Link Frequency
urine 2
ileum 1
M cells 1
domes 1
INPP5K (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 10 75.12 Quite High
Piles 20 74.32 Quite High
interstitial cystitis 2 74.00 Quite High
Pain 4 72.48 Quite High
Multiple sclerosis 5 67.88 Quite High
Inflammation 56 62.52 Quite High
Inflammatory response 5 5.00 Very Low Very Low Very Low
tolerance 5 5.00 Very Low Very Low Very Low
Osteoarthritis 5 5.00 Very Low Very Low Very Low
metalloproteinase 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Inflammatory Bowel Disease 240 98.96 Very High Very High Very High
Ileitis 40 97.92 Very High Very High Very High
Disease 96 97.84 Very High Very High Very High
Congenital Anomalies 15 92.16 High High
Frailty 50 91.32 High High
Colon Disease 10 87.44 High High
Appetite Loss 2 80.20 Quite High
Granuloma 10 78.40 Quite High
Colitis 15 75.12 Quite High
INFLAMMATION 55 74.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is unknown whether variations in the macroscopic appearance of PPs have any relationship to patients’ susceptibility to disease or to the presence of disease.
Localization (appearance) of PPs associated with disease
1) Confidence 0.74 Published 2010 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2831089 Disease Relevance 1.49 Pain Relevance 0.14
According to the classification that we previously proposed, the macroscopic appearance of PPs was divided into two categories: type E, consisting of a nodular or convoluted elevation pattern; and type F, consisting of a flat pattern [6].
Localization (appearance) of PPs
2) Confidence 0.70 Published 2010 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2831089 Disease Relevance 0.91 Pain Relevance 0.16
In summary, orally administered PPS was very poorly absorbed, with the majority of the drug being excreted in faeces as intact PPS and in urine as low molecular weight and desulfated PPS.
Localization (excreted) of PPS in urine
3) Confidence 0.66 Published 2005 Journal Xenobiotica Section Abstract Doc Link 16278190 Disease Relevance 0.14 Pain Relevance 0.14
In summary, orally administered PPS was very poorly absorbed, with the majority of the drug being excreted in faeces as intact PPS and in urine as low molecular weight and desulfated PPS.
Localization (excreted) of PPS in urine
4) Confidence 0.66 Published 2005 Journal Xenobiotica Section Abstract Doc Link 16278190 Disease Relevance 0.15 Pain Relevance 0.15
This is the first study to document the detailed macroscopic appearance of PPs in the terminal ileum of UC patients using magnified endoscopy.
Localization (appearance) of PPs in ileum associated with inflammatory bowel disease
5) Confidence 0.65 Published 2010 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2831089 Disease Relevance 0.74 Pain Relevance 0
In addition, M cells could be detected in the FAE located on the PPs’ domes using electron microscopic examination of targeted biopsy samples targeted.
Localization (located) of PPs in domes
6) Confidence 0.65 Published 2010 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2831089 Disease Relevance 0.37 Pain Relevance 0
Our experience indicates that target biopsy under magnifying endoscopy and chromoendoscopy is beneficial for accurate biopsy sampling to obtain M cells, because this allows us to clearly recognize the FAE located on the PPs’ domes.
Localization (located) of PPs in M cells
7) Confidence 0.65 Published 2010 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2831089 Disease Relevance 0.44 Pain Relevance 0
Clusters are then allocated by PPS to each camp, and finally are coupled into implicit stratification pairs, and the odd triplet.

1.4.

Localization (allocated) of PPS
8) Confidence 0.62 Published 2007 Journal Emerg Themes Epidemiol Section Body Doc Link PMC1904216 Disease Relevance 0.08 Pain Relevance 0
The MMC, established as described above, were maintained in culture for 3 days in the presence of PPS, HA, dextran sulfate (DS) or heparin at concentrations of 0.0, 0.1, 0.5, 1.0, 2.5, 5.0, 10.0 and 20.0 ?
Localization (presence) of PPS
9) Confidence 0.51 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2875662 Disease Relevance 0 Pain Relevance 0

General Comments

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