INT131468

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Context Info
Confidence 0.00
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (POMC) signal transducer activity (MC1R) cell-cell signaling (POMC)
cytoplasm (POMC) pigmentation (MC1R) extracellular space (POMC)
Anatomy Link Frequency
melanocyte 2
POMC (Homo sapiens)
MC1R (Homo sapiens)
Pain Link Frequency Relevance Heat
melanocortin 1 receptor 10 100.00 Very High Very High Very High
agonist 1 77.04 Quite High
antagonist 1 55.28 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Activation of MC1R by adrenocorticotrophin or alpha-melanocyte stimulating hormone is positively coupled to the cAMP signaling pathway and leads to a stimulation of melanogenesis and a switch from the synthesis of pheomelanins to the production of eumelanic pigments.
Positive_regulation (leads) of stimulating hormone Positive_regulation (Activation) of MC1R in melanocyte associated with melanocortin 1 receptor
1) Confidence 0.00 Published 2005 Journal Pigment Cell Res. Section Abstract Doc Link 16280005 Disease Relevance 0 Pain Relevance 0.74

General Comments

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