INT131475

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.31
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 2.01
Pain Relevance 1.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Hspa1b) mitochondrion (Hspa1b) nucleus (Hspa1b)
intracellular (Hspa1b) protein complex (Hspa1b) response to stress (Hspa1b)
Anatomy Link Frequency
liver 1
Hspa1b (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 26 99.80 Very High Very High Very High
Disease Link Frequency Relevance Heat
Shock 2 100.00 Very High Very High Very High
Targeted Disruption 14 99.44 Very High Very High Very High
Hepatotoxicity 12 98.96 Very High Very High Very High
Heat Stress Disorders 4 96.36 Very High Very High Very High
Sprains And Strains 6 58.48 Quite High
Fever 2 36.16 Quite Low
Injury 2 25.00 Low Low
Toxicity 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect of the inducible forms of 70 kDa heat shock protein (Hsp70i) on acetaminophen (APAP) hepatotoxicity was assessed in an Hsp70i knockout mouse model.
Regulation (effect) of Hsp70i associated with targeted disruption, paracetamol, shock and hepatotoxicity
1) Confidence 0.31 Published 2006 Journal Toxicol. Appl. Pharmacol. Section Abstract Doc Link 16280147 Disease Relevance 0.94 Pain Relevance 0.53
Absence of the Hsp70i protein in liver was verified by monitoring Hsp levels in knockout and control mice after heat stress (41.5 degrees C water bath immersion for 30 min).
Regulation (Absence) of Hsp70i in liver associated with targeted disruption and heat stress disorders
2) Confidence 0.19 Published 2006 Journal Toxicol. Appl. Pharmacol. Section Abstract Doc Link 16280147 Disease Relevance 1.07 Pain Relevance 0.61

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox