INT131476

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Context Info
Confidence 0.30
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.07
Pain Relevance 0.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Hspa1b) mitochondrion (Hspa1b) nucleus (Hspa1b)
intracellular (Hspa1b) protein complex (Hspa1b) response to stress (Hspa1b)
Anatomy Link Frequency
liver 1
Hspa1b (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 13 97.40 Very High Very High Very High
Disease Link Frequency Relevance Heat
Targeted Disruption 7 99.44 Very High Very High Very High
Hepatotoxicity 6 98.04 Very High Very High Very High
Heat Stress Disorders 2 96.36 Very High Very High Very High
Shock 1 95.80 Very High Very High Very High
Sprains And Strains 3 58.48 Quite High
Fever 1 36.16 Quite Low
Injury 1 25.00 Low Low
Toxicity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Absence of the Hsp70i protein in liver was verified by monitoring Hsp levels in knockout and control mice after heat stress (41.5 degrees C water bath immersion for 30 min).
Negative_regulation (Absence) of Hsp70i in liver associated with targeted disruption and heat stress disorders
1) Confidence 0.30 Published 2006 Journal Toxicol. Appl. Pharmacol. Section Abstract Doc Link 16280147 Disease Relevance 1.07 Pain Relevance 0.61

General Comments

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