INT1315

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Context Info
Confidence 0.38
First Reported 1977
Last Reported 1994
Negated 0
Speculated 0
Reported most in Title
Documents 3
Total Number 3
Disease Relevance 0.16
Pain Relevance 2.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transducer activity (Gnrhr) cell-cell signaling (Pomc) cytoplasm (Pomc)
extracellular space (Pomc) generation of precursor metabolites and energy (Pomc) signal transduction (Pomc)
Pomc (Rattus norvegicus)
Gnrhr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Clonidine 10 100.00 Very High Very High Very High
narcan 6 100.00 Very High Very High Very High
Morphine 2 99.92 Very High Very High Very High
opiate 5 99.22 Very High Very High Very High
Opioid 2 98.72 Very High Very High Very High
agonist 1 94.20 High High
antagonist 5 88.08 High High
Enkephalin 1 87.76 High High
Central nervous system 1 71.76 Quite High
opioid receptor 1 52.56 Quite High
Disease Link Frequency Relevance Heat
Body Weight 2 83.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Multiple opiate receptor subtypes are involved in the stimulation of growth hormone release by beta-endorphin in female rats.
beta-endorphin Positive_regulation (stimulation) of Localization (release) of growth hormone associated with opiate
1) Confidence 0.38 Published 1994 Journal Neuroendocrinology Section Title Doc Link 8090284 Disease Relevance 0 Pain Relevance 0.55
Beta-endorphin mediates clonidine stimulated growth hormone release.
Beta-endorphin Positive_regulation (mediates) of Localization (release) of growth hormone associated with narcan and clonidine
2) Confidence 0.18 Published 1989 Journal Neuroendocrinology Section Title Doc Link 2572990 Disease Relevance 0.16 Pain Relevance 1.08
Stimulation in vivo of the secretion of prolactin and growth hormone by beta-endorphin.
beta-endorphin Positive_regulation (Stimulation) of Localization (secretion) of growth hormone associated with narcan
3) Confidence 0.11 Published 1977 Journal Endocrinology Section Title Doc Link 187406 Disease Relevance 0 Pain Relevance 0.53

General Comments

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