INT131505

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Context Info
Confidence 0.55
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.39
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Rac1, Trpv1) intracellular (Rac1) enzyme binding (Rac1)
GTPase activity (Rac1) lipid metabolic process (Trpv1) cytoplasm (Rac1)
Anatomy Link Frequency
peripheral neuron 2
Rac1 (Rattus norvegicus)
Trpv1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Nerve growth factor 9 97.88 Very High Very High Very High
Pain 1 97.36 Very High Very High Very High
Root ganglion neuron 1 71.24 Quite High
Disease Link Frequency Relevance Heat
Acquired Immune Deficiency Syndrome Or Hiv Infection 1 99.72 Very High Very High Very High
Pain 1 97.36 Very High Very High Very High
Ganglion Cysts 1 70.92 Quite High
Pheochromocytoma 1 69.44 Quite High
Nociception 1 50.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We conclude that the Rac1/NADPH oxidase pathway regulates p38 activation and TRPV1 expression which aids in the maintenance of peripheral neuron integrity and pain perception.
Rac1 Regulation (regulates) of Gene_expression (expression) of TRPV1 in peripheral neuron associated with pain and acquired immune deficiency syndrome or hiv infection
1) Confidence 0.55 Published 2005 Journal J. Neurochem. Section Abstract Doc Link 16283857 Disease Relevance 0.39 Pain Relevance 0.42

General Comments

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