INT131508

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Context Info
Confidence 0.42
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.21
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Rac1, Trpv1) intracellular (Rac1) enzyme binding (Rac1)
GTPase activity (Rac1) lipid metabolic process (Trpv1) cytoplasm (Rac1)
Rac1 (Rattus norvegicus)
Trpv1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Nerve growth factor 9 100.00 Very High Very High Very High
Pain 1 79.52 Quite High
Root ganglion neuron 1 79.28 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 1 78.96 Quite High
Pheochromocytoma 1 77.48 Quite High
Nociception 1 58.12 Quite High
Pain 1 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Inhibition of NADPH oxidase by transient transfection of a dominant negative Rac1 mutant (RacN17) plasmid blocked NGF-stimulated TRPV1 protein expression, while expression of a constitutively active Rac1 increased basal and NGF-stimulated TRPV1 levels.
Gene_expression (expression) of Rac1 Positive_regulation (increased) of TRPV1 associated with nerve growth factor
1) Confidence 0.42 Published 2005 Journal J. Neurochem. Section Abstract Doc Link 16283857 Disease Relevance 0.21 Pain Relevance 0.48

General Comments

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