INT131513

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Context Info
Confidence 0.25
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.64
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Cnr1) plasma membrane (Cnr1) response to stress (Cnr1)
signal transducer activity (Cnr1)
Anatomy Link Frequency
output neurons 1
RVM 1
Cnr1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Cannabinoid receptor 3 100.00 Very High Very High Very High
Antinociceptive 1 99.64 Very High Very High Very High
Rostral ventromedial medulla 5 99.16 Very High Very High Very High
Central grey 8 96.68 Very High Very High Very High
Endocannabinoid 5 88.88 High High
tail-flick 1 66.56 Quite High
agonist 1 46.16 Quite Low
qutenza 1 45.44 Quite Low
Pain 2 25.00 Low Low
analgesia 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 8 96.68 Very High Very High Very High
Nociception 5 75.00 Quite High
Pain 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the ventrolateral periaqueductal gray (PAG), activation of excitatory output neurons projecting monosynaptically to OFF cells in the rostral ventromedial medulla (RVM) causes antinociceptive responses and is under the control of cannabinoid receptor type-1 (CB1) and vanilloid transient receptor potential vanilloid type 1 (TRPV1) receptors.
Regulation (under) of in RVM Regulation (control) of CB1 in output neurons associated with cannabinoid receptor, antinociceptive, central grey and rostral ventromedial medulla
1) Confidence 0.25 Published 2006 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 16284279 Disease Relevance 0.64 Pain Relevance 0.60

General Comments

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