INT131584

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Context Info
Confidence 0.33
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.70
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (PDIA3) protein folding (PDIA3) signal transduction (PDIA3)
endoplasmic reticulum (PDIA3)
Anatomy Link Frequency
MDA-MB-231 1
PDIA3 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 2 89.44 High High
Clonidine 2 75.12 Quite High
agonist 5 50.48 Quite High
dopamine receptor 2 30.72 Quite Low
Dopamine 6 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
bradykinin 2 5.00 Very Low Very Low Very Low
Opioid 2 5.00 Very Low Very Low Very Low
opioid receptor 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Malignant Neoplastic Disease 1 100.00 Very High Very High Very High
Cancer 6 98.56 Very High Very High Very High
Stress 1 70.92 Quite High
Bordatella Infection 2 5.00 Very Low Very Low Very Low
Osteoarthritis 2 5.00 Very Low Very Low Very Low
Heart Rate Under Development 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ERp57 shRNA co-expression with the ?
Gene_expression (expression) of ERp57
1) Confidence 0.33 Published 2010 Journal J Mol Signal Section Body Doc Link PMC2954983 Disease Relevance 0 Pain Relevance 0
Hek293 cells were tested for the expression of each chaperone tested (figure 1b) and Bip, Calnexin, Calreticulin, ERp57, HSP70, PDI and GRP94 were all expressed.
Gene_expression (expressed) of ERp57
2) Confidence 0.25 Published 2010 Journal J Mol Signal Section Body Doc Link PMC2954983 Disease Relevance 0 Pain Relevance 0
A single subtype was expressed in malignant HS-578T (alpha(2A)) and MDA-MB-231 and non-tumour MCF-10A cells (alpha(2B)).
Gene_expression (expressed) of HS-578T in MDA-MB-231 associated with malignant neoplastic disease and cancer
3) Confidence 0.03 Published 2006 Journal Cancer Chemother. Pharmacol. Section Abstract Doc Link 16292538 Disease Relevance 0.70 Pain Relevance 0.15

General Comments

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