INT131609

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Context Info
Confidence 0.24
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.33
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Tbxa2r) signal transducer activity (Tbxa2r)
Anatomy Link Frequency
mesenteric artery 1
Tbxa2r (Rattus norvegicus)
Pain Link Frequency Relevance Heat
COX2 2 98.06 Very High Very High Very High
Clonidine 8 85.52 High High
Inflammation 26 83.04 Quite High
aspirin 44 81.92 Quite High
COX-2 inhibitor 3 77.40 Quite High
antagonist 14 75.00 Quite High
Inflammatory response 5 25.00 Low Low
agonist 14 5.00 Very Low Very Low Very Low
Serotonin 7 5.00 Very Low Very Low Very Low
corticosteroid 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Respiratory Disease 84 100.00 Very High Very High Very High
INFLAMMATION 34 83.04 Quite High
Occupational Lung Diseases 2 80.08 Quite High
Coagulation Disorder 4 76.44 Quite High
Malaria 4 75.00 Quite High
Hypersensitivity 4 68.88 Quite High
Asthma 29 56.64 Quite High
Rhinitis 19 46.72 Quite Low
Insect Bites And Stings 1 25.00 Low Low
Bites And Stings 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Orchidectomy modulates alpha2-adrenoceptor reactivity in rat mesenteric artery through increased thromboxane A2 formation.
thromboxane A2 Binding (formation) of in mesenteric artery associated with cox2
1) Confidence 0.24 Published 2006 Journal J. Vasc. Res. Section Title Doc Link 16293968 Disease Relevance 0 Pain Relevance 0.39
TBXA2R +795T > C was associated with AERD susceptibility in a Korean population.46 Further, the -19993T > C SNP in the TBX21 promoter region was associated with AERD in a Japanese population.47 These findings were not replicated in a Korean population.48
TBXA2R Binding (associated) of associated with respiratory disease
2) Confidence 0.04 Published 2009 Journal Yonsei Medical Journal Section Body Doc Link PMC2796398 Disease Relevance 0.95 Pain Relevance 0.08
Unlike any previously characterized members of the D7 family, AnSt-D7L1 has acquired the important function of binding thromboxane A2 (TXA2) and its analogs with high affinity.
thromboxane A2 Binding (binding) of
3) Confidence 0.02 Published 2010 Journal PLoS Biology Section Abstract Doc Link PMC2994686 Disease Relevance 0.38 Pain Relevance 0.08

General Comments

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