INT131649

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Context Info
Confidence 0.44
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.32
Pain Relevance 0.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Slc6a4) endosome (Slc6a4) transport (Slc6a4)
plasma membrane (Slc6a4)
Anatomy Link Frequency
hippocampus 2
Slc6a4 (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 5 100.00 Very High Very High Very High
Raphe 5 97.32 Very High Very High Very High
Nucleus accumbens 1 95.32 Very High Very High Very High
Serotonin 38 93.72 High High
fluoxetine 15 83.36 Quite High
depression 1 33.88 Quite Low
monoamine 2 5.00 Very Low Very Low Very Low
primary somatosensory cortex 1 5.00 Very Low Very Low Very Low
Thalamus 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 5 82.12 Quite High
Schizophrenia 1 36.00 Quite Low
Anxiety Disorder 1 34.64 Quite Low
Depression 1 33.88 Quite Low
Handedness 12 5.00 Very Low Very Low Very Low
Ganglion Cysts 3 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low
Adhesions 1 5.00 Very Low Very Low Very Low
Vibrio Infection 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Together, these results suggest that a low estrogen state increases SERT activity in the hippocampus despite an apparent reduction in SERT density.
Positive_regulation (increases) of Negative_regulation (reduction) of SERT in hippocampus associated with hippocampus
1) Confidence 0.44 Published 2005 Journal Brain Res. Section Abstract Doc Link 16298349 Disease Relevance 0.32 Pain Relevance 0.72
Zic2-positive but not Zic2-negative RGC axons respond to pharmacological blockage of Sert
Positive_regulation (respond) of Negative_regulation (blockage) of Sert
2) Confidence 0.42 Published 2010 Journal EMBO J Section Body Doc Link PMC2944059 Disease Relevance 0 Pain Relevance 0.19

General Comments

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