INT131654

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Context Info
Confidence 0.36
First Reported 2005
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 2.38
Pain Relevance 0.81

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell death (Olr1) extracellular region (Olr1) cell adhesion (Olr1)
plasma membrane (Olr1) cellular_component (Olr1)
Anatomy Link Frequency
plasma 2
chest 2
Olr1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Angina 15 99.60 Very High Very High Very High
Disease Link Frequency Relevance Heat
Angina 12 99.60 Very High Very High Very High
Atherosclerotic Plaque 2 98.16 Very High Very High Very High
Diabetes Mellitus 2 97.36 Very High Very High Very High
Coronary Artery Disease 10 96.36 Very High Very High Very High
Atherosclerosis 4 95.16 Very High Very High Very High
Obesity 2 92.88 High High
Cv General 3 Under Development 3 64.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Oxidation of LDL induces production of autoantibodies against oxLDL (oxLDLab) that can be measured using an EIA test.
Positive_regulation (induces) of Gene_expression (production) of oxLDL
1) Confidence 0.36 Published 2005 Journal Free Radic. Biol. Med. Section Abstract Doc Link 16298691 Disease Relevance 0.96 Pain Relevance 0.29
Increased levels of oxLDL autoantibodies are associated with severe chest pain attacks in nondiabetic patients with CHD.
Positive_regulation (Increased) of Gene_expression (levels) of oxLDL in chest associated with angina and coronary artery disease
2) Confidence 0.33 Published 2005 Journal Free Radic. Biol. Med. Section Abstract Doc Link 16298691 Disease Relevance 1.29 Pain Relevance 0.52
CONCLUSION: In each Braunwald class of UAP, elevated plasma levels of ox-LDL closely relate to the presence of angiographically detected complex and thrombotic lesion morphology.


Positive_regulation (elevated) of Gene_expression (levels) of ox-LDL in plasma
3) Confidence 0.19 Published 2007 Journal Circ. J. Section Body Doc Link 17456991 Disease Relevance 0.13 Pain Relevance 0

General Comments

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