INT131760

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Context Info
Confidence 0.02
First Reported 2006
Last Reported 2007
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.29
Pain Relevance 0.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (P2rx6)
Anatomy Link Frequency
choroid plexus 1
P2rx6 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
substance P 1 100.00 Very High Very High Very High
nMDA receptor 1 96.80 Very High Very High Very High
opioid receptor 1 95.52 Very High Very High Very High
Opioid 3 94.64 High High
dorsal root ganglion 6 93.32 High High
Spinal cord 2 89.24 High High
agonist 7 82.44 Quite High
Neuropeptide 1 82.40 Quite High
Neurotransmitter 3 80.84 Quite High
narcan 1 55.72 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 6 93.32 High High
Cystic Fibrosis 8 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 4 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low
Disorders Of The Lacrimal System 1 5.00 Very Low Very Low Very Low
Age-related Macular Degeneration 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
GeneChip analysis revealed that neither estrogen nor contraction alone changed the mRNA expression of substance P, the neurokinin-1 receptor, CGRP, NGF, the P2X3 receptor, GABAA and GABAB, the 5-HT3A and 5-HT3B receptor, N-methyl-D-aspartate and non-N-methyl-D-aspartate receptors, opioid receptors, and opioid-like receptor.
Transcription (expression) of P2X3 receptor associated with nmda receptor, opioid receptor, opioid and substance p
1) Confidence 0.02 Published 2006 Journal J. Appl. Physiol. Section Abstract Doc Link 16306253 Disease Relevance 0.29 Pain Relevance 0.82
RT-PCR experiments have determined the expression of mRNA for P2X1, P2X2, P2X4, P2X5 P2X6 and P2X7 in choroid plexus [94,95] (Table 1).
Spec (determined) Transcription (expression) of P2X5 P2X6 in choroid plexus
2) Confidence 0.02 Published 2007 Journal Cerebrospinal Fluid Res Section Body Doc Link PMC2072944 Disease Relevance 0 Pain Relevance 0.04

General Comments

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