INT131817

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Context Info
Confidence 0.02
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 1.59
Pain Relevance 1.85

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

methyltransferase activity (Asmt) cellular_component (Asmt)
Asmt (Mus musculus)
Pain Link Frequency Relevance Heat
COX-2 inhibitor 12 100.00 Very High Very High Very High
Hyperalgesia 12 98.18 Very High Very High Very High
Inflammation 18 87.76 High High
Analgesic 3 51.28 Quite High
Disease Link Frequency Relevance Heat
Hyperalgesia 12 98.18 Very High Very High Very High
INFLAMMATION 9 87.76 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Injection of endotoxin (10 mg kg(-1), i.p.) to mice elicited hyperalgesia, determined by hot plate test, which is prevented by NO precursor (L-arginine), cNOS/iNOS inhibitor (N(G)-nitro-L-arginine methyl ester; L-NAME), NF-kappaB inhibitor (N-acetylserotonin), COX inhibitor (indomethacin), COX-2 inhibitor (DFU) and PARS inhibitor (3-aminobenzamide).
Negative_regulation (inhibitor) of N-acetylserotonin associated with hyperalgesia and cox-2 inhibitor
1) Confidence 0.02 Published 2006 Journal Pharmacol. Res. Section Abstract Doc Link 16310374 Disease Relevance 0.53 Pain Relevance 0.60
Injection of endotoxin (10 mg kg(-1), i.p.) to mice elicited hyperalgesia, determined by hot plate test, which is prevented by NO precursor (L-arginine), cNOS/iNOS inhibitor (N(G)-nitro-L-arginine methyl ester; L-NAME), NF-kappaB inhibitor (N-acetylserotonin), COX inhibitor (indomethacin), COX-2 inhibitor (DFU) and PARS inhibitor (3-aminobenzamide).
Negative_regulation (inhibitor) of N-acetylserotonin associated with hyperalgesia and cox-2 inhibitor
2) Confidence 0.02 Published 2006 Journal Pharmacol. Res. Section Abstract Doc Link 16310374 Disease Relevance 0.52 Pain Relevance 0.59
Injection of endotoxin (10 mg kg(-1), i.p.) to mice elicited hyperalgesia, determined by hot plate test, which is prevented by NO precursor (L-arginine), cNOS/iNOS inhibitor (N(G)-nitro-L-arginine methyl ester; L-NAME), NF-kappaB inhibitor (N-acetylserotonin), COX inhibitor (indomethacin), COX-2 inhibitor (DFU) and PARS inhibitor (3-aminobenzamide).
Negative_regulation (inhibitor) of N-acetylserotonin associated with hyperalgesia and cox-2 inhibitor
3) Confidence 0.02 Published 2006 Journal Pharmacol. Res. Section Abstract Doc Link 16310374 Disease Relevance 0.53 Pain Relevance 0.66

General Comments

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